UCD Cancer Data Lab
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proteomics
Experimental reproducibility limits the correlation between mRNA and protein abundances in tumour proteomic profiles
Large-scale studies of human proteomes have revealed only a moderate correlation between mRNA and protein abundances. It is unclear to …
Swathi Ramachandra Upadhya
,
Colm J. Ryan
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Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma
The clinical management of locally advanced oesophageal adenocarcinoma (OAC) involves neoadjuvant chemoradiotherapy (CRT), but as …
Simone Marcone
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Amy Buckley
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Colm J. Ryan
,
Mark McCabe
,
Niamh Lynam-Lennon
,
David Matallanas
,
OSullivan Jacintha
,
Susan Kennedy
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Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness
Osteosarcoma (OS) is an aggressive sarcoma, where novel treatment approaches are required. Genomic studies suggest that a subset of OS, …
Harriett Holme
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Aditi Gulati
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Rachel Brough
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Emmy DG Fleuren
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Ilirjana Bajrami
,
James Campbell
,
Irene Y Chong
,
Sara Costa-Cabral
,
Richard Elliott
,
Tim Fenton
,
others
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A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events
Protein complexes are responsible for the bulk of activities within the cell, but how their behavior and abundance varies across tumors …
Colm J. Ryan
,
Susan Kennedy
,
Ilirjana Bajrami
,
David Matallanas
,
Christopher J Lord
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