DAISY: picking synthetic lethals from cancer genomes

Abstract

A better understanding of genetic interactions in cancer might help identify new therapeutic approaches that exploit the concept of synthetic lethality. Ruppin and colleagues have developed a new computational method, DAISY, that predicts such interactions and potentially facilitates the delineation and validation of comprehensive genetic interaction networks.

Publication
Cancer Cell
Colm J. Ryan
Colm J. Ryan
Associate Professor