Complex synthetic lethality in cancer
Targeting synthetic lethal paralogs in cancer
Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma
Cross-species identification of PIP5K1-, splicing-and ubiquitin-related pathways as potential targets for RB1-deficient cells
Accurate prediction of kinase-substrate networks using knowledge graphs
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS&#7475&#185&#179&#7472
Cells lacking the RB1 tumor suppressor gene are hyperdependent on Aurora B kinase for survival
Synthetic Lethality and Cancer – Penetrance as the Major Barrier
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness
Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer
E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer
A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events
Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast
The histone variant H2A. Z promotes splicing of weak introns
ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
Large-scale profiling of kinase dependencies in cancer cell lines
Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast
Evolutionarily conserved genetic interactions with budding and fission yeast &#119872&#119906&#119905&#119878 identify orthologous relationships in mismatch repair-deficient cancer cells
DAISY: picking synthetic lethals from cancer genomes
Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function
Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae
High-resolution network biology: connecting sequence with function
Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation
The yeast SR-like protein Npl3 links chromatin modification to mRNA processing
Hierarchical Modularity and the Evolution of Genetic Interactomes across Species
Key Functional Regions in the Histone Variant H2A.Z C-Terminal Docking Domain
Improved functional overview of protein complexes using inferred epistatic relationships
Imputing and predicting quantitative genetic interactions in epistatic MAPs
Missing value imputation for epistatic MAPs