3

Benchmarking Genetic Interaction Scoring Methods for Identifying Synthetic Lethality from Combinatorial CRISPR Screens
Synthetic lethality (SL) is an extreme form of negative genetic interaction, where simultaneous disruption of two non-essential genes …
Cite DOI Preprint Source Code Data
Evaluating Sequence and Structural Similarity Metrics for Predicting Shared Paralog Functions
Gene duplication is the primary source of new genes, resulting in most genes having identifiable paralogs. Over evolutionary time …
Cite DOI Preprint Source Code Data