Nevan J Krogan

Latest

• High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe
• The histone variant H2A. Z promotes splicing of weak introns
• Evolutionarily conserved genetic interactions with budding and fission yeast &#119872&#119906&#119905&#119878 identify orthologous relationships in mismatch repair-deficient cancer cells
• High-resolution network biology: connecting sequence with function
• All or nothing: protein complexes flip essentiality between distantly related eukaryotes
• The yeast SR-like protein Npl3 links chromatin modification to mRNA processing
• Comparative interaction networks: bridging genotype to phenotype
• Key Functional Regions in the Histone Variant H2A.Z C-Terminal Docking Domain
• Improved functional overview of protein complexes using inferred epistatic relationships
• Imputing and predicting quantitative genetic interactions in epistatic MAPs